|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRTIs |
|
Country
|
Thailand; South Africa; India; Malawi;Tanzania |
Literature Information
|
PubMed PMID
|
27704010
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2016 |
|
Journal
|
Open forum infectious diseases |
|
Title
|
Human Immunodeficiency Virus-1 Sequence Changes and Drug Resistance Mutation Among Virologic Failures of Lopinavir/Ritonavir Monotherapy: AIDS Clinical Trials Group Protocol A5230. |
|
Author
|
Vardhanabhuti S,Katzenstein D,Bartlett J,Kumarasamy N,Wallis CL |
|
Evidence
|
At VF, the majority of RT mutations presented at SE were lost: only 26% (7 of 27) of the participants retained the M184V/I and 22% (4 of 18) retained the Y181C.
|
|
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HIV Mutation Detail Information