HIV Mutation Detail Information

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Mutation Information
Mutation Site Y181C
Mutation Type Amino acid level
Gene/Protein/Region Type RT
Genotype/Subtype A;C;D;DA
Relevant Drug efavirenz (EFV);nevirapine (NPV)
Country Kenya
Literature Information
PubMed PMID 27231099
Disease HIV infection/AIDS
Published Year 2016
Journal Journal of the International AIDS Society
Title Treatment failure and drug resistance in HIV-positive patients on tenofovir-based first-line antiretroviral therapy in western Kenya.
Author Brooks K,Diero L,DeLong A,Balamane M,Reitsma M,Kemboi E,Orido M,Emonyi W,Coetzer M,Hogan J,Kantor R
Evidence Mutations associated with K65R included Y181C (19/24, 79%, with K65R vs. 2/11, 18%, without;p=0.002); G190A/S (12/24, 50%, with K65R vs. 1/11, 9%, without;p=0.027);and G190A/Y181C co-occurrence (9/24, 38% with K65R vs. 0/11 without;p=0.033).

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation