|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.Y181C+rt.G190S |
|
Genotype/Subtype
|
A;CRF02_AG |
|
Relevant Drug
|
efavirenz (EFV);nevirapine (NPV) |
|
Country
|
Russia |
Literature Information
|
PubMed PMID
|
25259833
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2014 |
|
Journal
|
AIDS (London, England) |
|
Title
|
A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. |
|
Author
|
Kolomeets AN,Varghese V,Lemey P,Bobkova MR,Shafer RW |
|
Evidence
|
The next most common NNRTI-resistance mutations in subtype AFSU viruses were K103N (25 patients), Y181C (13 patients), G190A (8 patients), A98G (4 patients), V108I (3 patients), and Y188L (2 patients).
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HIV Mutation Detail Information