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Mutation Information
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Mutation Site
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Y181C |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
efavirenz (EFV);nevirapine (NPV);lamivudine (LAM);emtricitabine (FTC);stavudine (D4T);zidovudine (AZT);tenofovir (TDF);abacavir (ABC);didanosine (DDI);emtricitabine (FTC);entecavir (ETV) |
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Country
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Togo |
Literature Information
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PubMed PMID
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21663632
|
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Disease
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HIV infection/AIDS
|
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Published Year
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2011 |
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Journal
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Journal of the International AIDS Society |
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Title
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High prevalence of HIV-1 drug resistance among patients on first-line antiretroviral treatment in Lomé, Togo. |
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Author
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Dagnra AY,Vidal N,Mensah A,Patassi A,Aho K,Salou M,Monleau M,Prince-David M,Singo A,Pitche P,Delaporte E,Peeters M |
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Evidence
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Importantly, eight patients were already predicted to be resistant to etravirine, the new NNRTI, either because they harboured the single Y181V mutation (n = 3) or due to the presence of both Y181C and H221Y mutations (n = 5).
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HIV Mutation Detail Information