HIV Mutation Detail Information

> Y181C Search Result

Mutation Information

Mutation Site	Y181C
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	A;D
Relevant Drug	nevirapine (NPV)
Country	Uganda

Literature Information

PubMed PMID	21655245
Disease	HIV infection/AIDS
Published Year	2011
Journal	PloS one
Title	Emergence and persistence of minor drug-resistant HIV-1 variants in Ugandan women after nevirapine single-dose prophylaxis.
Author	Hauser A,Mugenyi K,Kabasinguzi R,Kuecherer C,Harms G,Kunz A
Evidence	Methods and FindingsNVP-resistant HIV-1 harbouring the K103N and/or Y181C resistance mutations in the HIV-1 reverse transcriptase gene was measured from 1 week up to 18 months after NVP single-dose prophylaxis in 29 Ugandan women using allele-specific PCR assays capable of detecting drug-resistant variants representing less than 1% of the whole viral population.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation