|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
NNRITs |
|
Country
|
Cambodia |
Literature Information
|
PubMed PMID
|
20578491
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2010 |
|
Journal
|
The Southeast Asian journal of tropical medicine and public health |
|
Title
|
Virologic and immunologic outcomes in HIV-infected Cambodian children after 18 months of highly active antiretroviral therapy (HAART). |
|
Author
|
Sophan S,Meng CY,Pean P,Harwell J,Hutton E,Trzmielina S,Somasundaran M,Luzuriaga K,Pugatch D |
|
Evidence
|
Genotypic resistance typing in 2 children with PVL >400 copies/ml at 18 months demonstrated mutations associated with resistance to lamivudine (M184V) and non-nucleoside reverse transcriptase inhibitors (Y181C and G190A).
|
|
|
HIV Mutation Detail Information