HIV Mutation Detail Information

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Mutation Information

Mutation Site	Y181C
Mutation Type	Amino acid level
Gene/Protein/Region Type	RT
Genotype/Subtype	CRF01_AE
Relevant Drug	zidovudine (AZT);nevirapine (NVP);didanosine (DDI)
Country	Thailand

Literature Information

PubMed PMID	20158398
Disease	HIV infection/AIDS
Published Year	2010
Journal	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America
Title	Efficacy and safety of 1-month postpartum zidovudine-didanosine to prevent HIV-resistance mutations after intrapartum single-dose nevirapine.
Author	Lallemant M,Ngo-Giang-Huong N,Jourdain G,Traisaithit P,Cressey TR,Collins IJ,Jarupanich T,Sukhumanant T,Achalapong J,Sabsanong P,Chotivanich N,Winiyakul N,Ariyadej S,Kanjanasing A,Ratanakosol J,Hemvuttiphan J,Kengsakul K,Wannapira W,Sittipiyasakul V,Pornkitprasarn W,Liampongsabuddhi P,McIntosh K,Van Dyke RB,Frenkel LM,Koetsawang S,Le Coeur S,Kanchana S,PHPT-4 Study Team.
Evidence	Consensus sequencing and the more sensitive oligonucleotide ligation assay (OLA) were performed on samples drawn at 7-10, 37-45 and 120 days postpartum (if VL>500 copies/mL) to detect K103N/Y181C/G190A mutations.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation