|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Combined Mutation
|
rt.Y181C+rt.K103N |
|
Relevant Drug
|
NNRTIs |
Literature Information
|
PubMed PMID
|
20102271
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2010 |
|
Journal
|
The Journal of infectious diseases |
|
Title
|
Pre-existing minority drug-resistant HIV-1 variants, adherence, and risk of antiretroviral treatment failure. |
|
Author
|
Paredes R,Lalama CM,Ribaudo HJ,Schackman BR,Shikuma C,Giguel F,Meyer WA 3rd,Johnson VA,Fiscus SA,D'Aquila RT,Gulick RM,Kuritzkes DR,AIDS Clinical Trials Group (ACTG) A5095 Study Team. |
|
Evidence
|
Minority K103N or Y181C populations were determined by allele-specific PCR (ASPCR) in subjects without NNRTI resistance by population sequencing.
|
|
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HIV Mutation Detail Information