|
Mutation Information
|
Mutation Site
|
Y181C |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Relevant Drug
|
etravirine (ETR) |
Literature Information
|
PubMed PMID
|
20010074
|
|
Published Year
|
2010 |
|
Journal
|
AIDS (London, England) |
|
Title
|
N348I in HIV-1 reverse transcriptase decreases susceptibility to tenofovir and etravirine in combination with other resistance mutations. |
|
Author
|
Sluis-Cremer N,Moore K,Radzio J,Sonza S,Tachedjian G |
|
Evidence
|
However, N348I significantly decreases tenofovir susceptibility when combined with thymidine analogue mutations and etravirine susceptibility when combined with Y181C.
|
|
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HIV Mutation Detail Information