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Mutation Information
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Mutation Site
|
Y180E |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
BZLF1 |
Literature Information
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PubMed PMID
|
16940523
|
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Published Year
|
2006 |
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Journal
|
Journal of virology |
|
Title
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Amino acids in the basic domain of Epstein-Barr virus ZEBRA protein play distinct roles in DNA binding, activation of early lytic gene expression, and promotion of viral DNA replication. |
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Author
|
Heston L,El-Guindy A,Countryman J,Dela Cruz C,Delecluse HJ,Miller G |
|
Evidence
|
Three late mutants, with a Y180A, Y180E, or K188A mutation, were defective at stimulating EBV DNA replication.
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EBV Mutation Detail Information