Mutation Information
Mutation Site
|
Y169A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
CA |
Literature Information
PubMed PMID
|
32858867
|
Published Year
|
2020 |
Journal
|
Viruses |
Title
|
HIV-1 Maturation: Lessons Learned from Inhibitors. |
Author
|
Kleinpeter AB,Freed EO |
Evidence
|
(D) The Y169A mutation (blue) phenocopies the effect of CAI on the conformation of the dimer interface (PDB accession 3DS2). PF74 and other inhibitors perturb the CA-NTD/CA-CTD CA interface.
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