HIV Mutation Detail Information

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Mutation Information

Mutation Site	Y143R
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN
Viral Reference	HXB2
Relevant Drug	bictegravir (BIC);dolutegravir (DTG);elvitegravir (EVG);raltegravir (RAL)
Country	USA

Literature Information

PubMed PMID	33800269
Disease	HIV infection/AIDS
Published Year	2021
Journal	International journal of environmental research and public health
Title	Short Communication: Integrase Strand Transfer Inhibitors Drug Resistance Mutations in Puerto Rico HIV-Positive Individuals.
Author	López P,Tirado G,Arias A,Sánchez R,Rodríguez-López ER,Rivera-Amill V
Evidence	We identified the Q148HKR, G140S, Y143R, N155H, S147G, and E138EA major drug resistance mutations and the D232DN, T97TA, E157Q, G163GART accessory mutations.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation