HIV Mutation Detail Information

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Mutation Information
Mutation Site Y143R
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Country Kenya
Literature Information
PubMed PMID 32116431
Disease HIV infection/AIDS
Published Year 2020
Journal Ethiopian journal of health sciences
Title Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya.
Author Mabeya S,Nyamache A,Ngugi C,Nyerere A,Lihana R
Evidence All 188 sequences were analysed for HV-1 drug resistance. From analysis of these integrase sequences, no primary mutations (Y143R=C=H, Q148H=R=K, and N155H=S) associated with reduced susceptibility to the integrase inhibitors Raltegravir and Elvitegravir were detected.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation