HIV Mutation Detail Information

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Mutation Information

Mutation Site	Y143R
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN
Country	Kenya

Literature Information

PubMed PMID	32116431
Disease	HIV infection/AIDS
Published Year	2020
Journal	Ethiopian journal of health sciences
Title	Characterization of HIV-1 Integrase Gene and Resistance Associated Mutations Prior to Roll out of Integrase Inhibitors by Kenyan National HIV-Treatment Program in Kenya.
Author	Mabeya S,Nyamache A,Ngugi C,Nyerere A,Lihana R
Evidence	All 188 sequences were analysed for HV-1 drug resistance. From analysis of these integrase sequences, no primary mutations (Y143R=C=H, Q148H=R=K, and N155H=S) associated with reduced susceptibility to the integrase inhibitors Raltegravir and Elvitegravir were detected.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation