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Mutation Information
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Mutation Site
|
Y143R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
INSTIs |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
30461149
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2019 |
|
Journal
|
HIV medicine |
|
Title
|
Prevalence and determinants of resistance mutations in HIV-1-infected patients exposed to integrase inhibitors in a large Italian cohort. |
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Author
|
Modica S,Rossetti B,Lombardi F,Lagi F,Maffeo M,D'Autilia R,Pecorari M,Vicenti I,Bruzzone B,Magnani G,Paolucci S,Francisci D,Penco G,Sacchini D,Zazzi M,De Luca A,Di Biagio A |
|
Evidence
|
The most frequent INSTI resistance mutation was N155H, followed by Q148H/K/R, G140A/C/S, E138A/K/T and Y143C/H/R.
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HIV Mutation Detail Information