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Mutation Information
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Mutation Site
|
Y143R |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
IN |
|
Relevant Drug
|
INSTIs |
|
Country
|
Turkey |
Literature Information
|
PubMed PMID
|
27125365
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2016 |
|
Journal
|
HIV clinical trials |
|
Title
|
Integrase Strand Transfer Inhibitors (INSTIs) Resistance Mutations in HIV-1 Infected Turkish Patients. |
|
Author
|
Sayan M,Gündüz A,Ersöz G,İnan A,Deveci A,Özgür G,Sargın F,Karagöz G,İnci A,İnan D,Ülçay A,Karaoğlan I,Kaya S,Kutlu SS,Süer K,Çağatay A,Akalın H |
|
Evidence
|
However, ARV-experienced patients had major resistance mutations associated with raltegravir and elvitegravir;the following results were generated:F121Y, Y143R, Q148R and E157Q (6/91 - 6.6%).
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HIV Mutation Detail Information