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Mutation Information
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Mutation Site
|
Y143H |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
IN |
Literature Information
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PubMed PMID
|
18687142
|
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Published Year
|
2008 |
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Journal
|
Retrovirology |
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Title
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Natural variation of HIV-1 group M integrase: implications for a new class of antiretroviral inhibitors. |
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Author
|
Rhee SY,Liu TF,Kiuchi M,Zioni R,Gifford RJ,Holmes SP,Shafer RW |
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Evidence
|
Nearly all INI-resistance mutations known to directly reduce HIV-1 susceptibility were nonpolymorphic including H51Y, T66I, E92Q, F121Y, G140S, Y143C/H/R, Q146P, S147G, Q148H/R/K, S153Y, N155H/S, and R263K.
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HIV Mutation Detail Information