HIV Mutation Detail Information

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Mutation Information

Mutation Site	Y143C
Mutation Type	Amino acid level
Gene/Protein/Region Type	IN
Country	Caucasian;sub-Saharan Africa

Literature Information

PubMed PMID	32259255
Disease	HIV infection/AIDS
Published Year	2020
Journal	The Journal of antimicrobial chemotherapy
Title	Characterization of viral rebounds on dual etravirine/raltegravir maintenance therapy (ANRS-163 ETRAL trial).
Author	Soulie C,Assoumou L,Abdi B,Sayon S,Nguyen T,Valantin MA,Beniguel L,Ferre V,Alloui C,Montes B,Avettand-Fenoel V,Delaugerre C,Descamps D,Martinez E,Reynes J,Peytavin G,Costagliola D,Katlama C,Calvez V,Marcelin AG,ANRS-163 ETRAL study group.
Evidence	Some RT variants became dominant at VF (K101E, 86.3%;Y181C, 100.0%;G190A, 100.0%) and others emerged in integrase (Y143C, 2.4%;Q148R, 6.2%;N155H, 18.8%).

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation