HIV Mutation Detail Information

> Y143C Search Result


Mutation Information
Mutation Site Y143C
Mutation Type Amino acid level
Gene/Protein/Region Type IN
Viral Reference Q76353
Relevant Drug raltegravir (RAL)
Literature Information
PubMed PMID 31551948
Disease HIV infection/AIDS
Published Year 2019
Journal Frontiers in microbiology
Title Raltegravir-Induced Adaptations of the HIV-1 Integrase: Analysis of Structure, Variability, and Mutation Co-occurrence.
Author Machado LA,Gomes MFDC,Guimarães ACR
Evidence Curiously, four isolates showed mutations related to more than one of the three main resistance pathways: two from Italy, one with both N155H and Y143R and another with Q148H and Y143H;one from Canada with N155H and Y143C;and one from France with N155H and Q148R.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation