|
Mutation Information
|
Mutation Site
|
Y135L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
Nef |
|
Genotype/Subtype
|
B |
|
Country
|
USA |
Literature Information
|
PubMed PMID
|
30249546
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2018 |
|
Journal
|
EBioMedicine |
|
Title
|
Impact of a single HLA-A*24:02-associated escape mutation on the detrimental effect of HLA-B*35:01 in HIV-1 control. |
|
Author
|
Murakoshi H,Koyanagi M,Akahoshi T,Chikata T,Kuse N,Gatanaga H,Rowland-Jones SL,Oka S,Takiguchi M |
|
Evidence
|
We also found a Nef Y135L mutation in approximately 8% of the HLA-B*35:01+ individuals (data not shown) although this mutation did not appear to be associated with specific HLA alleles.
|
|
|
HIV Mutation Detail Information