|
Mutation Information
|
Mutation Site
|
Y134N |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.Y134N+s.S132A;s.G145R+s.Y134N |
|
Country
|
Turkey |
Literature Information
|
PubMed PMID
|
20382061
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2010 |
|
Journal
|
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases |
|
Title
|
Monitoring of hepatitis B virus surface antigen escape mutations and concomitantly nucleos(t)ide analog resistance mutations in Turkish patients with chronic hepatitis B. |
|
Author
|
Sayan M,Sentürk O,Akhan SÇ,Hülagü S,Cekmen MB |
|
Evidence
|
In the NUC therapy group the prevalence was 8.5% (12/142), with the following patterns: sY100C+sI110V, sL109I, sP120T, sP127T, sG130R+sG145X, sS132A+sY134N, sY134N+sG145R, sC137G, sD144E, sG145R.
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HBV Mutation Detail Information