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Mutation Information
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Mutation Site
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Y115F |
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Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
abacavir (ABC) |
|
Country
|
Burkina Faso |
Literature Information
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PubMed PMID
|
30079168
|
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Disease
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HIV infection/AIDS
|
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Published Year
|
2018 |
|
Journal
|
Journal of public health in Africa |
|
Title
|
Human immunodeficiency virus type 1 drug resistance in a subset of mothers and their infants receiving antiretroviral treatment in Ouagadougou, Burkina Faso. |
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Author
|
Soubeiga ST,Bazie BVJTE,Compaore TR,Ouattara AK,Zohoncon TM,Obiri-Yeboah D,Yonli AT,Zongo A,Traore L,Pietra V,Akpona S,Diagbouga S,Simpore J |
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Evidence
|
The drugs affected by these mutations were AZT (T215F/Y, D67N/E);3TC (M184V, T215F/Y, D67N/E), FTC (M184V), ABC (M184V) and TDF (T215F/Y). Also, other DRM such as K70R (5.56%), K219Q (5.56%), T69D (5.56%), Y115F (5.56%) and K65R (5.56%) were detected with equal rates in mothers and were associated with resistance to (AZT, 3TC, TDF), 3TC, DDI, ABC and 3TC respectively.
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HIV Mutation Detail Information