Mutation Information
Mutation Site
|
Y115F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Relevant Drug
|
NRTIs |
Country
|
Russia |
Literature Information
PubMed PMID
|
25259833
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2014 |
Journal
|
AIDS (London, England) |
Title
|
A uniquely prevalent nonnucleoside reverse transcriptase inhibitor resistance mutation in Russian subtype A HIV-1 viruses. |
Author
|
Kolomeets AN,Varghese V,Lemey P,Bobkova MR,Shafer RW |
Evidence
|
One or more of the non-TAMs, K65R/N, L74V/I, and Y115F were present in 1.4% (n = 3), 26% (n = 16), and 9.2% (n = 8) of patients receiving thymidine-alog, nonthymidine-alog, and both thymidine-alog and nonthymidine-alog regimens.
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