Mutation Information
Mutation Site
|
Y100C |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
D |
Country
|
Italy |
Literature Information
PubMed PMID
|
24700252
|
Disease
|
HBV-HIV coinfection
|
Published Year
|
2014 |
Journal
|
Infection |
Title
|
HBV whole-genome mutation profile in HIV-1/HBV coinfected patients in a long-term follow-up study. |
Author
|
Taffon S,Genovese D,Blasi M,Pierotti P,Degli Esposti A,Catone S,Chionne P,Pulimanti B,Candido A,Dettori S,Tosti ME,Argentini C,Mazzotta F,Rapicetta M |
Evidence
|
Known mutants Y100C, P127T and P120A associated to Y134H and S143T and new S mutants, which may potentially affect HBsAg expression and secretion and anti-HBs binding, were detected in baseline sera persisting up to the end of 9 years follow-up.
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