|
Mutation Information
|
Mutation Site
|
W88G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
RT |
|
Viral Reference
|
K03455.1
|
|
Relevant Drug
|
foscarnet |
Literature Information
|
PubMed PMID
|
16524459
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2006 |
|
Journal
|
BMC infectious diseases |
|
Title
|
DR_SEQAN: a PC/Windows-based software to evaluate drug resistance using human immunodeficiency virus type 1 genotypes. |
|
Author
|
Garriga C,Menéndez-Arias L |
|
Evidence
|
However, DR_SEQAN assumes the effects of mutations such as W88G, E89K or E89G that confer resistance to foscarnet while increasing AZT susceptibility, or K20T whose antagonist effect on amprenavir resistance has been demonstrated.
|
|
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HIV Mutation Detail Information