HBV Mutation Detail Information

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Mutation Information

Mutation Site	W74*
Mutation Type	Amino acid level
Gene/Protein/Region Type	S
Country	China

Literature Information

PubMed PMID	30906435
Disease	Chronic hepatitis B
Published Year	2019
Journal	Experimental and therapeutic medicine
Title	Viral quasispecies of hepatitis B virus in patients with YMDD mutation and lamivudine resistance may not predict the efficacy of lamivudine/adefovir rescue therapy.
Author	Wang C,Yu S,Zhang Y,Zhang M,Lv L,Huang C,Li X,Li J,Zhang Z
Evidence	Furthermore, three out of five stop codons in the S region (sS34, sW74, sW172, sW182, sW196) were identified in the RT region; the stop codons have been associated with NAs resistance, also affected the HBsAg reading frame (rtA181T/sW172, rtV191I/sW182* and rtM204I/sW196*).

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation