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Mutation Information
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Mutation Site
|
W54R |
|
Mutation Type
|
Amino acid level |
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Gene/Protein/Region Type
|
Vpr |
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Genotype/Subtype
|
G |
Literature Information
|
PubMed PMID
|
32753492
|
|
Published Year
|
2020 |
|
Journal
|
mBio |
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Title
|
HIV Vpr Modulates the Host DNA Damage Response at Two Independent Steps to Damage DNA and Repress Double-Strand DNA Break Repair. |
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Author
|
Li D,Lopez A,Sandoval C,Nichols Doyle R,Fregoso OI |
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Evidence
|
These include HIV-1 W54R/HIV-2 L59A Vpr mutants, which block the ability of HIV-1 Vpr to recruit and degrade the DNA glycosylase UNG2
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HIV Mutation Detail Information