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Mutation Information
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Mutation Site
|
W29G |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
BARF1 |
|
Viral Reference
|
V01555.2
|
|
Country
|
Indonesia |
Literature Information
|
PubMed PMID
|
20849661
|
|
Disease
|
Nasopharyngeal carcinoma
|
|
Published Year
|
2010 |
|
Journal
|
Infectious agents and cancer |
|
Title
|
Conserved mutation of Epstein-Barr virus-encoded BamHI-A Rightward Frame-1 (BARF1) gene in Indonesian nasopharyngeal carcinoma. |
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Author
|
Hutajulu SH,Hoebe EK,Verkuijlen SA,Fachiroh J,Hariwijanto B,Haryana SM,Stevens SJ,Greijer AE,Middeldorp JM |
|
Evidence
|
The W29G mutation is providing more flexibility to a beta sheet element inside the BARF1 molecule normally stabilized by hydrophobic interactions. It is uncertain to what extent this substitutions affects the overall BARF1 structure.
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EBV Mutation Detail Information