HBV Mutation Detail Information

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Mutation Information

Mutation Site	W28*
Mutation Type	Amino acid level
Gene/Protein/Region Type	PreC
Country	Korea

Literature Information

PubMed PMID	23071796
Disease	Hepatocellular carcinoma
Published Year	2012
Journal	PloS one
Title	Naturally occurring precore/core region mutations of hepatitis B virus genotype C related to hepatocellular carcinoma.
Author	Kim DW,Lee SA,Hwang ES,Kook YH,Kim BJ
Evidence	Six (preC-W28, C-P5H/L/T, C-E83D, C-I97F/L, C-L100I and C-Q182K/) and seven types (preC-W28*, preC-G29D, C-D32N/H, C-E43K, C-P50A/H/Y, C-A131G/N/P and C-S181H/P) of mutations in the preC/C region were found to be related to HCC and to affect the HBeAg serostatus, respectively.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation