HBV Mutation Detail Information

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Mutation Information

Mutation Site	W26*
Mutation Type	Amino acid level
Gene/Protein/Region Type	PreC
Amino acid_Mutation	G1891A

Literature Information

PubMed PMID	16549970
Disease	HBV-HIV coinfection
Published Year	2006
Journal	AIDS (London, England)
Title	Characteristics of drug resistant HBV in an international collaborative study of HIV-HBV-infected individuals on extended lamivudine therapy.
Author	Matthews GV,Bartholomeusz A,Locarnini S,Ayres A,Sasaduesz J,Seaberg E,Cooper DA,Lewin S,Dore GJ,Thio CL
Evidence	Two further patients had pre-core mutations that result in truncations of the pre-core protein including one genotype A virus truncated at G1891A (W26 stop) and one with a 1-base pair deletion after 1839, resulting in a frame shift.

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Description

Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation