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Mutation Information
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Mutation Site
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W23L |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Vpu |
Literature Information
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PubMed PMID
|
17910056
|
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Published Year
|
2008 |
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Journal
|
Proteins |
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Title
|
Biophysical characterization of Vpu from HIV-1 suggests a channel-pore dualism. |
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Author
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Mehnert T,Routh A,Judge PJ,Lam YH,Fischer D,Watts A,Fischer WB |
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Evidence
|
Peptides corresponding to the TM domain of Vpu (Vpu1-32) and mutant peptides (Vpu1-32-W23L, Vpu1-32-R31V, Vpu1-32-S24L) have been synthesized and reconstituted into artificial lipid bilayers.
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HIV Mutation Detail Information