EBV Mutation Detail Information

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Mutation Information

Mutation Site	W227S
Mutation Type	Amino acid level
Gene/Protein/Region Type	EBNA3C

Literature Information

PubMed PMID	21440926
Published Year	2011
Journal	Virology
Title	Epstein-Barr virus nuclear protein 3C binds to the N-terminal (NTD) and beta trefoil domains (BTD) of RBP/CSL; only the NTD interaction is essential for lymphoblastoid cell growth.
Author	Calderwood MA,Lee S,Holthaus AM,Blacklow SC,Kieff E,Johannsen E
Evidence	Further, an EBNA3C WTP STP(W227S) mutation impaired BTD binding whereas EBNA3 homology domain mutations disrupted RBP/CSL N-terminal domain (NTD) binding.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation