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Mutation Information
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Mutation Site
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W209A |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Large T |
Literature Information
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PubMed PMID
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21454559
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Published Year
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2011 |
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Journal
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The Journal of biological chemistry |
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Title
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Merkel cell polyomavirus large T antigen disrupts lysosome clustering by translocating human Vam6p from the cytoplasm to the nucleus. |
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Author
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Liu X,Hein J,Richardson SC,Basse PH,Toptan T,Moore PS,Gjoerup OV,Chang Y |
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Evidence
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MCV LT alanine substitution mutants, GST.LT(1-258).R204A, T205A, Y206A, G207A, T208A, and W209A were generated using the QuikChange Lighting Site-directed Mutagenesis Kit (Agilent) using GST.
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MCV Mutation Detail Information