|
Mutation Information
|
Mutation Site
|
W182L |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Viral Reference
|
X85254.1;
M32138.1;
FJ904433.1;
AF121240.1;
X65259.1 |
|
Immune Escape
|
Y |
|
Country
|
Iran |
Literature Information
|
PubMed PMID
|
31105017
|
|
Disease
|
Hepatocellular carcinoma;
Liver cirrhosis
|
|
Published Year
|
2019 |
|
Journal
|
Annals of hepatology |
|
Title
|
Association of HBsAg mutation patterns with hepatitis B infection outcome: Asymptomatic carriers versus HCC/cirrhotic patients. |
|
Author
|
Hosseini SY,Sanaei N,Fattahi MR,Malek-Hosseini SA,Sarvari J |
|
Evidence
|
Although the frequency of T126S/R, G130K/R and W182L/* mutations were detected in 3 out of 19 of the HCC/cirrhotic group and none of the asymptomatic cases, they were not statistically significant (P >0.05). Also, I82T (N = 3), Q101R (N = 3), S207T/N/R (N = 5), P214L/Q (N = 4), C221Y (N = 3) and Y225S (N = 3) mutation was detected more prevalently in the asymptomatic group than those with HCC/cirrhosis, (P > 0.05).
|
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HBV Mutation Detail Information