|
Mutation Information
|
Mutation Site
|
W182* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.W182*+rt.V191I |
Literature Information
|
PubMed PMID
|
31218588
|
|
Published Year
|
2019 |
|
Journal
|
Virologica Sinica |
|
Title
|
Complementation of Wild-Type and Drug-Resistant Hepatitis B Virus Genomes to Maintain Viral Replication and Rescue Virion Production under Nucleos(t)ide Analogs. |
|
Author
|
Wu C,Li B,Zhang X,Zhao K,Chen Y,Yuan Y,Liu Y,Chen R,Xu D,Chen X,Lu M |
|
Evidence
|
In the present study, HBV genomes with frequently detected reverse transcriptase (RT)/surface truncation MTs, rtA181T/sW172*, rtV191I/sW182* and rtM204I/sW196*, were phenotypically characterized alone or together with their WT counterparts in different ratios by transient transfection in the absence or presence of NAs.
|
|
|
HBV Mutation Detail Information