Mutation Information
Mutation Site
|
W182* |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Country
|
France |
Literature Information
PubMed PMID
|
28822954
|
Disease
|
Acute exacerbation of chronic hepatitis B
|
Published Year
|
2017 |
Journal
|
Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology |
Title
|
The variability of hepatitis B envelope is associated with HBs antigen persistence in either chronic or acute HBV genotype A infection. |
Author
|
Eschlimann M,Malvé B,Velay A,Fenaux H,Berger S,Frippiat JP,Zoulim F,Bensenane M,Bronowicki JP,Goehringer F,May T,Jeulin H,Schvoerer E |
Evidence
|
Truncated proteins were observed in non-resolvers of different subgroups: in NR3 from AHBV subgroup (sW182stop at 4% in S gene and W4stop at 15% in preS), and in NR7b (sW182stop at 4% and sL216stop at 67% in S gene) and NR7c (sW163stop at 2% and sW182stop at 2% in S gene and W4stop at 5% and W52stop at 3% in preS region) from CHBV/HIV subgroup.
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