|
Mutation Information
|
Mutation Site
|
W172* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Amino acid_Mutation
|
G670A |
|
Country
|
china |
Literature Information
|
PubMed PMID
|
32840739
|
|
Disease
|
Chronic hepatitis B
|
|
Published Year
|
2020 |
|
Journal
|
Virus genes |
|
Title
|
An antiviral drug-resistant mutant of hepatitis B virus with high replication capacity in association with a large in-frame deletion in the preS1 region of viral surface gene. |
|
Author
|
Wang T,Qin Y,Zhang J,Li X,Tong S,Zhao W,Zhang J |
|
Evidence
|
The rtA181T mutation caused the W172* nonsense mutation in the overlapping S gene. In addition, all the clones harbored another nonsense mutation in the S gene (C69*) and a 207nt in-frame deletion in the preS1 region.
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|
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HBV Mutation Detail Information