|
Mutation Information
|
Mutation Site
|
W172* |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
S |
|
Combined Mutation
|
s.W172*+rt.A181T |
Literature Information
|
PubMed PMID
|
29609638
|
|
Published Year
|
2018 |
|
Journal
|
Virology journal |
|
Title
|
The truncated mutant HBsAg expression increases the tumorigenesis of hepatitis B virus by regulating TGF-β/Smad signaling pathway. |
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Author
|
Wang ML,Wu DB,Tao YC,Chen LL,Liu CP,Chen EQ,Tang H |
|
Evidence
|
BACKGROUND: It has been reported that the emergence of HBV rtA181T/sW172* mutant could result in a dominant secretion defect of HBsAg and increase the risk of HCC development.
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HBV Mutation Detail Information