HBV Mutation Detail Information

> W172* Search Result


Mutation Information
Mutation Site W172*
Mutation Type Amino acid level
Gene/Protein/Region Type S
Genotype/Subtype A
Country Spain
Literature Information
PubMed PMID 22666402
Disease Chronic hepatitis B
Published Year 2012
Journal PloS one
Title Ultra-deep pyrosequencing detects conserved genomic sites and quantifies linkage of drug-resistant amino acid changes in the hepatitis B virus genome.
Author Rodriguez-Frías F,Tabernero D,Quer J,Esteban JI,Ortega I,Domingo E,Cubero M,Camós S,Ferrer-Costa C,Sánchez A,Jardí R,Schaper M,Homs M,Garcia-Cehic D,Guardia J,Esteban R,Buti M
Evidence Of note, a substantial part of these substitutions (4 out of 9) resulted in stop codons (*) (sW156*, sW163*, sW165* and sW172*), giving rise to proteins with significant aa deletions.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation