Mutation Information
Mutation Site
|
W172* |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Combined Mutation
|
s.W172*+rt.A181T |
Literature Information
PubMed PMID
|
20516567
|
Published Year
|
2010 |
Journal
|
Antiviral therapy |
Title
|
Development of HBV S gene mutants in chronic hepatitis B patients receiving nucleotide/nucleoside analogue therapy. |
Author
|
Yeh CT |
Evidence
|
Among them, the rtA181T/sW172* mutant has a dominant negative secretion effect as well as an increased oncogenic potential.
|
|
|