HBV Mutation Detail Information

> W172* Search Result


Mutation Information
Mutation Site W172*
Mutation Type Amino acid level
Gene/Protein/Region Type S
Relevant Drug lamivudine (LAM);adefovir (ADV)
Literature Information
PubMed PMID 18331765
Disease HBV infection
Published Year 2008
Journal Journal of hepatology
Title Impact of hepatitis B virus rtA181V/T mutants on hepatitis B treatment failure.
Author Villet S,Pichoud C,Billioud G,Barraud L,Durantel S,Trépo C,Zoulim F
Evidence Since the S gene of HBV overlaps the polymerase gene, mutations in one gene may result in changes in the other gene. All the mutants harboring rtA181V and rtA181T mutations in the RT domain induced sL173F and sW172stop changes, respectively, in the S gene.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation