Mutation Information
Mutation Site
|
W172* |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
S |
Genotype/Subtype
|
Ayw |
Literature Information
PubMed PMID
|
10385663
|
Disease
|
HBV infection
|
Published Year
|
1999 |
Journal
|
Hepatology (Baltimore, Md.) |
Title
|
Mutational pattern of hepatitis B virus on sequential therapy with famciclovir and lamivudine in patients with hepatitis B virus reinfection occurring under HBIg immunoglobulin after liver transplantation. |
Author
|
Tillmann HL,Trautwein C,Bock T,Böker KH,Jäckel E,Glowienka M,Oldhafer K,Bruns I,Gauthier J,Condreay LD,Raab HR,Manns MP |
Evidence
|
One patient (NR21) selected a I68Nand P120Tcorresponding to mutations N424K and T476N within theHBV-DNA polymerase, 2 patients (R03, PR11) selected aE164D corresponding to a V521L mutation within theHBV-DNA polymerase, 1 (R02) selected a Q120P mutationon FCV, and another 1 (R04) selected a W172Stop mutation of the HBsAg corresponding to a A529T mutation within theHBV-DNA polymerase
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