HTLV1 Mutation Detail Information

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Mutation Information

Mutation Site	V89A
Mutation Type	Amino acid level
Gene/Protein/Region Type	Tax
Viral Reference	AB038239

Literature Information

PubMed PMID	21552325
Published Year	2011
Journal	PLoS pathogens
Title	NF-κB hyper-activation by HTLV-1 tax induces cellular senescence, but can be alleviated by the viral anti-sense protein HBZ.
Author	Zhi H,Yang L,Kuo YL,Ho YK,Shih HM,Giam CZ
Evidence	HeLa cells were transduced with lentivirus vectors carrying the EGFP (GFP) gene and wild-type and mutant tax alleles (H43Q, V85A, V89A, M22 [T130A, L131S], and M47 [L319R, L320S]) respectively at an MOI of 5, grown for 72 hours, and then harvested.

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Mutation Information Note

Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)

Literature Information Note

Evidence: sentence contains this mutation information in the citation