Mutation Information
Mutation Site
|
V82F |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
IN |
Country
|
Africa |
Literature Information
PubMed PMID
|
30891603
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2019 |
Journal
|
The Journal of antimicrobial chemotherapy |
Title
|
High predictive efficacy of integrase strand transfer inhibitors in perinatally HIV-1-infected African children in therapeutic failure of first- and second-line antiretroviral drug regimens recommended by the WHO. |
Author
|
Mboumba Bouassa RS,Mossoro-Kpinde CD,Gody JC,Veyer D,Péré H,Matta M,Robin L,Grésenguet G,Charpentier C,Bélec L |
Evidence
|
The distribution of DRMs and the polymorphism in RT and P genes are depicted in the Figure 2. DRMs to PIs corresponded mainly to natural polymorphism in the P gene while only the major DRMs V82A/F (n = 3;20%) and L33F (n = 1, 6.7%) could be found
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