HIV Mutation Detail Information

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Mutation Information
Mutation Site V82A
Mutation Type Amino acid level
Gene/Protein/Region Type PR
Genotype/Subtype B
Relevant Drug fosamprenavir (FPV);indinavir (IDV);lopinavir (LPV);nelfinavir (NFV);saquinavir (SQV)
Literature Information
PubMed PMID 30560871
Published Year 2018
Journal Scientific reports
Title Characterizing early drug resistance-related events using geometric ensembles from HIV protease dynamics.
Author Sheik Amamuddy O,Bishop NT,Tastan Bishop Ö
Evidence Additional research on multi-drug resistant HIV protease further described an expanded active site pocket and cavity expansion due to atomic volume for the HIV protease mutants V82A and I84V.

Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation