Mutation Information
Mutation Site
|
V82A |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
PR |
Literature Information
PubMed PMID
|
18597780
|
Published Year
|
2008 |
Journal
|
Journal of molecular biology |
Title
|
Effect of flap mutations on structure of HIV-1 protease and inhibition by saquinavir and darunavir. |
Author
|
Liu F,Kovalevsky AY,Tie Y,Ghosh AK,Harrison RW,Weber IT |
Evidence
|
Previously for atomic resolution structures of saquinavir complexes with wild type PR and mutants V82A and I84V and a 9X mutant with indinavir.
|
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