|
Mutation Information
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Mutation Site
|
V77I |
|
Mutation Type
|
Amino acid level |
|
Gene/Protein/Region Type
|
PR |
|
Combined Mutation
|
pr.V77I+pr.L63P |
|
Viral Reference
|
K02013.1
|
|
Relevant Drug
|
PIs |
|
Country
|
Italy |
Literature Information
|
PubMed PMID
|
11737863
|
|
Disease
|
HIV infection/AIDS
|
|
Published Year
|
2001 |
|
Journal
|
BMC microbiology |
|
Title
|
Analysis of HIV-1 drug resistant mutations by line probe assay and direct sequencing in a cohort of therapy naive HIV-1 infected Italian patients. |
|
Author
|
Re MC,Monari P,Bon I,Gibellini D,Vitone F,Borderi M,La Placa M |
|
Evidence
|
In particular, the most frequent substitutions, by genotyping analysis, are present at codon 36 [M36I alone (7 cases) or associated with L10V (2 cases)], at codon 63 [L63P alone (5 cases) or associated with V77I (2 cases)] and at codon 77 [V77I (5 cases)], while L10V was always found in association with A71V or M36I.
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HIV Mutation Detail Information