Mutation Information
Mutation Site
|
V75L |
Mutation Type
|
Amino acid level |
Gene/Protein/Region Type
|
RT |
Genotype/Subtype
|
AE |
Viral Reference
|
K03455.1
|
Country
|
China |
Literature Information
PubMed PMID
|
32102660
|
Disease
|
HIV infection/AIDS
|
Published Year
|
2020 |
Journal
|
BMC infectious diseases |
Title
|
Natural polymorphisms in HIV-1 CRF01_AE strain and profile of acquired drug resistance mutations in a long-term combination treatment cohort in northeastern China. |
Author
|
Sun Z,Ouyang J,Zhao B,An M,Wang L,Ding H,Han X |
Evidence
|
V75 L was correlated with known DRMs G190S (cKa/KsV75L-G190S = 3.24, LOD = infinity), K65R (cKa/KsK65R-V75L = 2.00, LOD = 5.04), and M184 V (cKa/KsV75L-M184V = 1.25, LOD = 4.03).
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