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Mutation Information
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Mutation Site
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V700L |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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BALF2 |
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Amino acid_Mutation
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C162215A |
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Viral Reference
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NC007605.1
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Country
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Guangzhou;China |
Literature Information
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PubMed PMID
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31209392
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Disease
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Nasopharyngeal carcinoma;
Burkitt lymphoma;
Hodgkin lymphoma;
NK/T cell lymphoma;
Gastric carcinoma
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Published Year
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2019 |
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Journal
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Nature genetics |
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Title
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Genome sequencing analysis identifies Epstein-Barr virus subtypes associated with high risk of nasopharyngeal carcinoma. |
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Author
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Xu M,Yao Y,Chen H,Zhang S,Cao SM,Zhang Z,Luo B,Liu Z,Li Z,Xiang T,He G,Feng QS,Chen LZ,Guo X,Jia WH,Chen MY,Zhang X,Xie SH,Peng R,Chang ET,Pedergnana V,Feng L,Bei JX,Xu RH,Zeng MS,Ye W,Adami HO,Lin X,Zhai W,Zeng YX,Liu J |
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Evidence
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We also investigated the association evidence for the recently reported EBER2 variants by Hui et al18 in our discovery dataset. NC_007605.1:7048A>C, which was a leading variant for the reported associations at EBER2 region, showed significant association in our genome-wide analysis (P = 1.25×10−7), but the significance was largely abolished by controlling for population structure (P = 1.52×10−2; Supplementary Fig. 6).
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EBV Mutation Detail Information