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Mutation Information
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Mutation Site
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V549E |
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Mutation Type
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Amino acid level |
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Gene/Protein/Region Type
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Gp41 |
Literature Information
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PubMed PMID
|
27992602
|
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Published Year
|
2016 |
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Journal
|
PLoS pathogens |
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Title
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Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer. |
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Author
|
Khasnis MD,Halkidis K,Bhardwaj A,Root MJ |
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Evidence
|
To determine if asymmetry in TOH structure is a definitive feature of HIV-1 resistance to C37, we also crystallized an N40/C37 construct containing the V549E substitution (Fig 6D, S1 Table).
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HIV Mutation Detail Information