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HIV Mutation Detail Information

> V549A Search Result


Mutation Information
Mutation Site V549A
Mutation Type Amino acid level
Gene/Protein/Region Type Gp41
Literature Information
PubMed PMID 27992602
Published Year 2016
Journal PLoS pathogens
Title Receptor Activation of HIV-1 Env Leads to Asymmetric Exposure of the gp41 Trimer.
Author Khasnis MD,Halkidis K,Bhardwaj A,Root MJ
Evidence We employed resistance mutations L544S and V549A that reside within the T20 binding site and decrease C-peptide interaction affinity 50-100 fold (Fig 1C).
Contents
Description
Mutation Information Note
  • Gene/Protein/Region Type: Virus Gene (e.g. LMP-1) or Virus Protein (e.g. Rep 68) or Virus Region (e.g. S, X)
Literature Information Note
  • Evidence: sentence contains this mutation information in the citation